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TMAO (Trimethylamine N-Oxide):

Fasting Required: Yes, 10-12 hours
Lab: Quest Diagnostics
Specimen: Blood
Results: Send out test to Cleveland Heart Clinic - Average processing time 5-7 days after send out lab receives.
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.

Patient Instructions: Refrain from consuming fish or other seafood the day before the blood draw to avoid false elevations.

Description: Gut microbes live symbiotically within the human digestive tract and play important roles in host defense, immunity, and nutrient processing and absorption. The diverse community is unique to each person and influenced by both acute and chronic dietary exposures to various food sources. Nutrients such as phosphatidylcholine (also known as lecithin), choline, and L-carnitine are abundant in animal-derived products such as red meat, egg yolk and full-fat dairy products. When consumed, these nutrients are processed by gut bacteria resulting in the release of various metabolites including TMA (trimethylamine) into the blood. TMA is then transported to the liver where it is converted into TMAO (trimethylamine N-oxide) which has been shown to regulate various physiological processes involved in the development of atherosclerosis.