Women's Health+-Genova Kit:
Note: This is a home collection test kit that will be mailed to you.
Fasting Required: No
Specimen: Saliva and Urine
Lab: Genova Diagnostics
Results: Average processing time 7-21 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.
Considerations:
Preparation & Timing: Plan to collect early in the workweek and ship within 2 days of collection.
Description: The Metabolomix+ is a unique combination of nutritional tests that provides an analysis of key nutritional biomarkers. A first morning void (FMV) urine collection, with optional add-on bloodspot finger stick and buccal swab, the Metabolomix+ nutritional test is a non-invasive, patient-friendly way to assess the functional need for antioxidants, B-vitamins, minerals, digestive support, fatty acids, and amino acids. Insights gained from the Metabolomix+ nutritional test allows clinicians to target nutritional therapies to the precise needs of their patients. Marked accumulation of organic acids in urine can signal a metabolic inhibition or block. The metabolic block may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect. Enzymes that are responsible for metabolizing organic acids are vitamin and mineral dependent. With this, elevations in organic acids can reflect a functional need for these nutrients on a cellular and biochemical level, even despite normal serum levels. Recommendations for nutrient supplementation based on elevated organic acid results are generated using a literature-based proprietary algorithm.
Traditionally, urinary organic acid assessment has been used in neonatal/pediatric medicine to identify genetic inborn errors of metabolism, with severity depending on the degree and type of error. In many cases of genetic inborn errors, the enzymatic defect may be compensated for by high doses of specific vitamin and mineral cofactors and/or dietary interventions. Intervention with higher-dose nutrient cofactors may also be effective in cases of decreased enzyme activity due to causes other than frank inborn errors.
The Women's Health+ report links each imbalance to evidence-informed levers you can pull immediately, such as stress-reduction tactics, adaptogens, food intake, methylation cofactors, and phytoestrogen or phytoandrogen support. You also get practical nutrient dosing suggestions derived from organic-acid patterns.
What Women's Health+ Measures:
Profile components:
Available Add-Ons to personalize methylation and phase I/II detox strategies (For an Additional Charge):
Fasting Required: No
Specimen: Saliva and Urine
Lab: Genova Diagnostics
Results: Average processing time 7-21 business days
Note: Result turnaround times are an estimate and are not guaranteed. Our reference lab may need additional time due to weather, holidays, confirmation/repeat testing, or equipment maintenance.
Considerations:
- Do not collect if there is blood in urine, including menstrual or other blood.
- Abnormal kidney function or use of diuretics may influence test results.
- Valproic acid, acetaminophen and berberine HCl are direct assay interferants for certain analytes.
Preparation & Timing: Plan to collect early in the workweek and ship within 2 days of collection.
- 24 hours leading up to urine collection consume no more than six 8-ounce glasses of fluid.
- 1 hour leading up to saliva collection or cheek swab do not eat, brush or floss your teeth, use mouthwash, or use lip balm, chewing gum, or any tobacco products. Drinking only water is okay during this time.
- Premenopausal women trying to evaluate ovulatory function should collect specimens between days 19 and 25 of their menstrual cycle. Males and peri/menopausal women can collect on any day.
- Patients on hormone therapies should wait to take hormone medication until after collecting the morning specimen, unless otherwise instructed by your clinician. Hormone levels are commonly tested 8-12 hours after a dose, but there are many factors to consider such as the type of medication, how you take it, how long you have been taking it, and your own body’s response to the medication. If you are taking synthetic or non-bioidentical hormones, results may be unpredictable. Consult your physician and ask if this test is right for you.
Description: The Metabolomix+ is a unique combination of nutritional tests that provides an analysis of key nutritional biomarkers. A first morning void (FMV) urine collection, with optional add-on bloodspot finger stick and buccal swab, the Metabolomix+ nutritional test is a non-invasive, patient-friendly way to assess the functional need for antioxidants, B-vitamins, minerals, digestive support, fatty acids, and amino acids. Insights gained from the Metabolomix+ nutritional test allows clinicians to target nutritional therapies to the precise needs of their patients. Marked accumulation of organic acids in urine can signal a metabolic inhibition or block. The metabolic block may be due to a nutrient deficiency, an inherited enzyme deficit, toxic build-up, or drug effect. Enzymes that are responsible for metabolizing organic acids are vitamin and mineral dependent. With this, elevations in organic acids can reflect a functional need for these nutrients on a cellular and biochemical level, even despite normal serum levels. Recommendations for nutrient supplementation based on elevated organic acid results are generated using a literature-based proprietary algorithm.
Traditionally, urinary organic acid assessment has been used in neonatal/pediatric medicine to identify genetic inborn errors of metabolism, with severity depending on the degree and type of error. In many cases of genetic inborn errors, the enzymatic defect may be compensated for by high doses of specific vitamin and mineral cofactors and/or dietary interventions. Intervention with higher-dose nutrient cofactors may also be effective in cases of decreased enzyme activity due to causes other than frank inborn errors.
The Women's Health+ report links each imbalance to evidence-informed levers you can pull immediately, such as stress-reduction tactics, adaptogens, food intake, methylation cofactors, and phytoestrogen or phytoandrogen support. You also get practical nutrient dosing suggestions derived from organic-acid patterns.
What Women's Health+ Measures:
- Salivary sex hormones: estradiol, estrone, progesterone, testosterone, DHEA, with an anabolic/catabolic snapshot.
- Diurnal HPA-axis rhythm: waking through evening cortisol with a need-for-support score.
- Urinary estrogen metabolism: pathway balance across 2-OH, 4-OH, and 16-OH estrogen metabolites plus methylation activity and 2:16 ratio to contextualize risk and guide clearance support.
- Urinary organic acids: functional markers tied to antioxidants, B-vitamins, mitochondrial function, methylation, dysbiosis, and detox needs, rolled into nutrient recommendations.
Profile components:
- Estrone, salivary
- Estradiol, salivary
- Estriol, salivary
- Progesterone, salivary
- Testosterone, salivary
- DHEA, salivary
- Cortisol, salivary
- 8-OHdG
- Estrogen & Estrogen Metabolites, urine
- Estrone, Urine
- Estradiol, urine
- Estriol, urine
- 2-Hydroxy(estrone + estradiol), urine
- 4-Hydroxy(estrone + estradiol), urine
- 2-Methoxy(estrone + estradiol), urine
- 4-Methoxy(estrone + estradiol), urine
- 16alpha-Hydroxyestrone, urine
- Creatinine
- Citric Acid
- Lactic Acid
- Pyruvic Acid
- Vanilmandelic Acid
- Homovanillic Acid
- 5-OH-Indoleacetic Acid
- D-Arabinitol
- Oxalate
- Organic Acids
Available Add-Ons to personalize methylation and phase I/II detox strategies (For an Additional Charge):
- MTHFR (Combined C677T & A1298C)
- COMT (V158M)
- CYP-1B1 (Combined L432V + N453S)
- CYP-1A1 (Combined MSPI & I462V)
- APOE